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TESOS (1 blister)
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Characteristics
Description
TESOS - PHARMACOM LABS
50 tabs x 0.5 mg (1 blister)
- Chemical name: (1R,2R,3S,5S)-3-(3,4-dichlorophenyl)-2-(ethoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane
- Formula: C17H23CL2N0
- Anabolic activity index: not a steroid
- Androgenic activity index: not a steroid
Tesofensine is an innovative Triple Serotonin Norepinephrine Dopamine Reuptake Inhibitor (SNDRI), representing a new generation of psychoactive antidepressants. This compound acts on vital neurotransmitters in the brain, including serotonin, norepinephrine, and dopamine. Initially developed by NeuroSearch A/S in Denmark, Tesofensine was originally designed to address the challenges posed by Parkinson's and Alzheimer's diseases.
Effects:
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Appetite Suppression: Tesofensine acts centrally to curb appetite, leading to a significant decrease in food cravings. Users typically experience a higher level of satiety and reduced desire to eat, often within a span of 14 days.
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Fat Oxidation and Adipose Tissue Reduction: Tesofensine substantially boosts fat oxidation and contributes to the reduction of adipose tissue, aiding in weight management.
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Insulin Sensitivity: This compound improves insulin sensitivity, which, in turn, enhances glucose metabolism, making it beneficial for individuals with metabolic concerns.
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Dopaminergic Receptor Alteration: Tesofensine has the capacity to modify the expression of dopaminergic receptors in the brain's striatum and influence their binding.
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Enhanced Energy Consumption: Users often report a significant increase in energy expenditure over a 14-day period.
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Extended Half-Life: Tesofensine boasts a prolonged half-life of 8-9 days, with primary metabolism occurring in the liver, where it forms the disalkyl metabolite M1 (NS-2360), the exclusive metabolite detected in human blood plasma.
Potential Side Effects:
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Gastrointestinal Distress: Some users may experience gastrointestinal issues, such as nausea, diarrhea, or constipation.
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Cardiovascular Effects: Tesofensine might have an impact on heart rate and blood pressure, potentially leading to adverse cardiovascular effects. Regular monitoring of these parameters is advisable.
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Psychological Effects: There is a possibility of psychological side effects, including mood changes, anxiety, or insomnia.
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Interactions: Tesofensine may interact with other medications or pre-existing medical conditions, necessitating careful consideration and medical guidance.
Dosage Instructions:
- A typical dosing regimen for Tesofensine may involve a daily intake, starting at lower doses, such as 0.5 mg or 1 mg, and gradually increasing as tolerated.
- Dosing may be adjusted based on individual response, but it is essential to adhere to recommended guidelines.
- Due to its long half-life, it is critical to maintain a consistent dosing schedule and avoid abrupt discontinuation.
Customer Reviews
Dialed down to .25mg/day and it's the sweet spot.
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